The “Weekend Effect” in patients admitted to the Emergency Unit with non-variceal upper gastrointestinal bleeding. A high-complexity hospital experience
DOI:
https://doi.org/10.22516/25007440.712Keywords:
Gastrointestinal hemorrhage, Endoscopy, Mortality, Weekend EffectAbstract
Introduction and Objectives: The “Weekend Effect” refers to an increase in mortality of patients admitted to health care centers on weekends or holidays. This study was performed to assess the impact of weekend admissions in patients with upper gastrointestinal bleeding (UGIB) based on a three year-experience in a high-complexity hospital in Latin America.
Materials and Methods: A descriptive observational study was performed between 2016 and 2018. Data on demographic characteristics, risk factors, symptoms, endoscopic findings, and medical treatment was described. Moreover, the time to perform an endoscopy, the length of hospital stay, and the mortality level among patients admitted on weekends were compared with the same factors during the week.
Results: The analysis included 274 patients admitted during the weekend and holidays (39.1%) versus patients admitted during the week (60.9%). The median age was 68.5 years old (interquartile range [IQR]: 53-79), and 56.6% were men. The most common conditions were tarry stools and hematemesis. Peptic ulcer was the most common endoscopic diagnosis (48.7%). Similar results were found in the length of hospital stay (7,38 ± 8,7 versus 7,38 ± 7,1; p = 0,234) and mortality groups (1,9 % versus 4,2 %; p = 0,274). A higher number of endoscopies 24 hours after the patient was admitted was performed (19,6 % versus 9,6 %; p = 0,041).
Conclusions: The “Weekend Effect” was not present in the analyzed group, and there are no significant differences related to the length of hospital stay or the mortality of patients diagnosed with UGIB.
Downloads
References
Barba R, Losa JE, Velasco M, Guijarro C, García de Casasola G, Zapatero A. Mortality among adult patients admitted to the hospital on weekends. Eur J Intern Med. 2006;17(5):322-4. https://doi.org/10.1016/j.ejim.2006.01.003
Becker DJ. Do hospitals provide lower quality care on weekends? Health Serv Res. 2007;42(4):1589-612. https://doi.org/10.1111/j.1475-6773.2006.00663.x
Bell CM, Redelmeier DA. Mortality among patients admitted to hospitals on weekends as compared with weekdays. N Engl J Med. 2001;345(9):663-8. https://doi.org/10.1056/NEJMsa003376
Fallah MA, Prakash C, Edmundowicz S. Acute gastrointestinal bleeding. Med Clin North Am. 2000;84(5):1183-208. https://doi.org/10.1016/s0025-7125(05)70282-0
Hearnshaw SA, Logan RF, Lowe D, Travis SP, Murphy MF, Palmer KR. Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit. Gut. 2011;60(10):1327-35. https://doi.org/10.1136/gut.2010.228437
Alvarado J, Suárez Y, García JA, Mosquera-Klinger G. Hemorragia de vías digestivas altas. En: Aponte D, Cañadas R (editores). Técnicas de endoscopia digestiva. 3.a edición. Bogotá: Panamericana; 2018. p. 339-49.
Laine L. CLINICAL PRACTICE. Upper Gastrointestinal Bleeding Due to a Peptic Ulcer. N Engl J Med. 2016;374(24):2367-76. https://doi.org/10.1056/NEJMcp1514257
Barkun AN, Almadi M, Kuipers EJ, Laine L, Sung J, Tse F, Leontiadis GI, Abraham NS, Calvet X, Chan FKL, Douketis J, Enns R, Gralnek IM, Jairath V, Jensen D, Lau J, Lip GYH, Loffroy R, Maluf-Filho F, Meltzer AC, Reddy N, Saltzman JR, Marshall JK, Bardou M. Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations From the International Consensus Group. Ann Intern Med. 2019;171(11):805-822. https://doi.org/10.7326/M19-1795
Gralnek IM. Evaluating the “weekend effect” on patient outcomes in upper GI bleeding. Gastrointest Endosc. 2014;80(2):236-8. https://doi.org/10.1016/j.gie.2014.04.004
Hwang JH, Fisher DA, Ben-Menachem T, Chandrasekhara V, Chathadi K, Decker GA, Early DS, Evans JA, Fanelli RD, Foley K, Fukami N, Jain R, Jue TL, Khan KM, Lightdale J, Malpas PM, Maple JT, Pasha S, Saltzman J, Sharaf R, Shergill AK, Dominitz JA, Cash BD; Standards of Practice Committee of the American Society for Gastrointestinal Endoscopy. The role of endoscopy in the management of acute non-variceal upper GI bleeding. Gastrointest Endosc. 2012;75(6):1132-8. https://doi.org/10.1016/j.gie.2012.02.033
Gupta A, Agarwal R, Ananthakrishnan AN. “Weekend Effect” in Patients With Upper Gastrointestinal Hemorrhage: A Systematic Review and Meta-analysis. Am J Gastroenterol. 2018;113(1):13-21. https://doi.org/10.1038/ajg.2017.430
Shih PC, Liu SJ, Li ST, Chiu AC, Wang PC, Liu LY. Weekend effect in upper gastrointestinal bleeding: a systematic review and meta-analysis. PeerJ. 2018;6:e4248. https://doi.org/10.7717/peerj.4248
Jairath V, Kahan BC, Logan RF, Hearnshaw SA, Travis SP, Murphy MF, Palmer KR. Mortality from acute upper gastrointestinal bleeding in the United kingdom: does it display a “weekend effect”? Am J Gastroenterol. 2011;106(9):1621-8. https://doi.org/10.1038/ajg.2011.172
Laine L, Jensen DM. Management of patients with ulcer bleeding. Am J Gastroenterol. 2012;107(3):345-60; quiz 361. https://doi.org/10.1038/ajg.2011.480
Shaheen AA, Kaplan GG, Myers RP. Weekend versus weekday admission and mortality from gastrointestinal hemorrhage caused by peptic ulcer disease. Clin Gastroenterol Hepatol. 2009;7(3):303-10. https://doi.org/10.1016/j.cgh.2008.08.033
Ananthakrishnan AN, McGinley EL, Saeian K. Outcomes of weekend admissions for upper gastrointestinal hemorrhage: a nationwide analysis. Clin Gastroenterol Hepatol. 2009;7(3):296-302e1. https://doi.org/10.1016/j.cgh.2008.08.013
Haas JM, Gundrum JD, Rathgaber SW. Comparison of time to endoscopy and outcome between weekend/weekday hospital admissions in patients with upper GI hemorrhage. WMJ. 2012;111(4):161-5.
Tufegdzic M, Panic N, Boccia S, Malerba S, Bulajic M, La Vecchia C, Sljivic A, Trbojevic-Stankovic J, Krstic M. The weekend effect in patients hospitalized for upper gastrointestinal bleeding: a single-center 10-year experience. Eur J Gastroenterol Hepatol. 2014;26(7):715-20. https://doi.org/10.1097/MEG.0000000000000124
Wu TC, Chuah SK, Chang KC, Wu CK, Kuo CH, Wu KL, Chiu YC, Hu TH, Tai WC. Outcome of holiday and nonholiday admission patients with acute peptic ulcer bleeding: a real-world report from southern Taiwan. Biomed Res Int. 2014;2014:906531. https://doi.org/10.1155/2014/906531
Khamaysi I, Gralnek IM. Nonvariceal Upper Gastrointestinal Bleeding: Timing of Endoscopy and Ways to Improve Endoscopic Visualization. Gastrointest Endosc Clin N Am. 2015;25(3):443-8. https://doi.org/10.1016/j.giec.2015.03.002
Lee JG, Turnipseed S, Romano PS, Vigil H, Azari R, Melnikoff N, Hsu R, Kirk D, Sokolove P, Leung JW. Endoscopy-based triage significantly reduces hospitalization rates and costs of treating upper GI bleeding: a randomized controlled trial. Gastrointest Endosc. 1999;50(6):755-61. https://doi.org/10.1016/s0016-5107(99)70154-9
Bjorkman DJ, Zaman A, Fennerty MB, Lieberman D, Disario JA, Guest-Warnick G. Urgent vs. elective endoscopy for acute non-variceal upper-GI bleeding: an effectiveness study. Gastrointest Endosc. 2004;60(1):1-8. https://doi.org/10.1016/s0016-5107(04)01287-8
Cho SH, Lee YS, Kim YJ, Sohn CH, Ahn S, Seo DW, et al. Outcomes and Role of Urgent Endoscopy in High-Risk Patients With Acute Nonvariceal Gastrointestinal Bleeding. Clin Gastroenterol Hepatol. 2018;16(3):370-377. https://doi.org/10.1016/j.cgh.2017.06.029
Lau JYW, Yu Y, Tang RSY, Chan HCH, Yip HC, Chan SM, Luk SWY, Wong SH, Lau LHS, Lui RN, Chan TT, Mak JWY, Chan FKL, Sung JJY. Timing of Endoscopy for Acute Upper Gastrointestinal Bleeding. N Engl J Med. 2020;382(14):1299-1308. https://doi.org/10.1056/NEJMoa1912484
Laursen SB, Leontiadis GI, Stanley AJ, Møller MH, Hansen JM, Schaffalitzky de Muckadell OB. Relationship between timing of endoscopy and mortality in patients with peptic ulcer bleeding: a nationwide cohort study. Gastrointest Endosc. 2017;85(5):936-944.e3. https://doi.org/10.1016/j.gie.2016.08.049

Downloads
Published
How to Cite
Issue
Section
License
Aquellos autores/as que tengan publicaciones con esta revista, aceptan los términos siguientes:
Los autores/as ceden sus derechos de autor y garantizarán a la revista el derecho de primera publicación de su obra, el cuál estará simultáneamente sujeto a la Licencia de reconocimiento de Creative Commons que permite a terceros compartir la obra siempre que se indique su autor y su primera publicación en esta revista.
Los contenidos están protegidos bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.

Article metrics | |
---|---|
Abstract views | |
Galley vies | |
PDF Views | |
HTML views | |
Other views |