Clinical, histological, and endoscopic characterization of gastric cancer at the Hospital de Especialidades Dr. Abel Gilbert Pontón, Ecuador
DOI:
https://doi.org/10.22516/25007440.558Keywords:
Gastric cancer, Gastric tumor, Gastric neoplasms, Gastric adenocarcinoma, Gastric histologyAbstract
Introduction: Gastric cancer is one of the most common causes of death worldwide, with a varying incidence. In Ecuador, it is the second leading cause of death in men and the fourth in women.
Objectives: To establish the socio-demographic, clinical, histological, and endoscopic characteristics of patients with gastric cancer and to determine the correlation between location and histology in this population treated at the Hospital de Especialidades Guayaquil Dr. Abel Gilbert Pontón.
Materials and methods: Analytical and prospective prevalence study. Outpatient and emergency upper gastrointestinal endoscopies with signs of suspected gastric cancer performed at the Hospital de Especialidades Guayaquil Dr. Abel Gilbert Pontón - Ecuador between January 2018 through December 2019 were included.
Results: The study included 62 patients diagnosed with gastric adenocarcinoma. 72.6% were male and 27.4% were female; the age range was between 27 and 95 years, with an average of 60.96 ± 15.1 years, the age of onset being between 60 and 70 years. Pain was the most frequent symptom in 98.4% of cases, followed by weight loss in 64.5%. The antrum was the most common site of cancer (50.0%), and Borrmann type III was the most common morphology. Intestinal cancer was found in 64.5% of cases, while diffuse gastric cancer was found in 29.0%. Intestinal cancer was more common in older ages (60-69%) and the most frequent site of presentation was the body of the stomach (71.4%) with a proximal location. In contrast, diffuse gastric cancer was more frequent in younger patients aged between 27-39 years, more often in the antrum (32.3%) at a more distal location.
Conclusions: Gastric cancer is more often found in men and is usually diagnosed in advanced stages. Intestinal gastric cancer was most commonly seen at advanced ages in our hospital, most frequently at the proximal site and in the Borrmann type III according to the classification of advanced gastric cancer, affecting its treatment and prognosis. The results obtained support the implementation of programs to diagnose and treat this severe disease in a timely manner.
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References
Cancer today [internet]. WHO, IARC; 2020 [consultado el 26 de abril de 2020]. Disponible en: https://gco.iarc.fr/today/online-analysis-pie?v=2020&mode=cancer&mode_population=continents&population=900&populations=900&key=total&sex=0&cancer=39&type=0&statistic=5&prevalence=0&population_group=0&ages_group%5B%5D=0&ages_group%5B%5D=17&nb_items=7&group_cancer=1&include_nmsc=1&include_nmsc_other=1&half_pie=0&donut=0
Ecuador [internet]. WHO, IARC; 2020 [consultado el 26 de abril de 2020]. Disponible en: https://gco.iarc.fr/today/data/factsheets/populations/218-ecuador-fact-sheets.pdf
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69-90. https://doi.org/10.3322/caac.20107
Torres J, Correa P, Ferreccio C, Hernandez-Suarez G, Herrero R, Cavazza-Porro M, et al. Gastric cancer incidence and mortality is associated with altitude in the mountainous regions of Pacific Latin America. Cancer Causes Control. 2013 Feb;24(2):249-56. https://doi.org/10.1007/s10552-012-0114-8
Coelho LG, León-Barúa R, Quigley EM. Latin-American Consensus Conference on Helicobacter pylori infection. Latin-American National Gastroenterological Societies affiliated with the Inter-American Association of Gastroenterology (AIGE). Am J Gastroenterol. 2000;95(10):2688-91. https://doi.org/10.1111/j.1572-0241.2000.03174.x
Camas y Egresos Hospitalarios [internet]. INEC; 2019 [consultado el 26 de abril de 2020]. Disponible en: https://www.ecuadorencifras.gob.ec/camas-y-egresos-hospitalarios/
Registro de Tumores SOLCA matriz [internet]. SOLCA; 2013 [consultado el 26 de abril de 2020]. Disponible en: http://www.estadisticas.med.ec/webpages/graficos.jsp
Estrategia nacional para la atención integral del cáncer en el Ecuador [internet]. Ministerio de Salud Pública del Ecuador; 2017 [consultado el 26 de abril de 2020]. Disponible en: https://aplicaciones.msp.gob.ec/salud/archivosdigitales/documentosDirecciones/dnn/archivos/ac_0059_2017.pdf
Corral Cordero F, Cueva Ayala P, Yépez Maldonado J, Tarupi Montenegro W. Trends in cancer incidence and mortality over three decades in Quito - Ecuador. Colomb Med (Cali). 2018;49(1):35-41. https://doi.org/10.25100/cm.v49i1.3785
Martínez-Galindo MG, Zamarripa-Dorsey F, Carmona-Castañeda A, Angeles-Labra A, Peñavera-Hernández R, Ugarte-Briones C, et al. Histopathologic characteristics of gastric adenocarcinoma in Mexican patients: a 10-year experience at the Hospital Juárez of Mexico. Rev Gastroenterol Mex. 2015;80(1):21-6. https://doi.org/10.1016/j.rgmx.2014.11.002
Bonequi P, Meneses-González F, Correa P, Rabkin CS, Camargo MC. Risk factors for gastric cancer in Latin America: a meta-analysis. Cancer Causes Control. 2013;24(2):217-31. https://doi.org/10.1007/s10552-012-0110-z
Sierra MS, Cueva P, Bravo LE, Forman D. Stomach cancer burden in Central and South America. Cancer Epidemiol. 2016;44 Suppl 1:S62-S73. https://doi.org/10.1016/j.canep.2016.03.008
Correa P. Cáncer gástrico: una enfermedad infecciosa. Revista Colombiana de Cirugía. 2011;26(2):111-7.
Andrade Díaz C. Análisis epidemiológico del cáncer gástrico en el Hospital de Especialidades Carlos Andrade Marín en el período enero-diciembre del año 2016. Revista Médica-Científica CAMbios HECAM. 2019;17(1):10-4. https://doi.org/10.36015/cambios.v17.n1.2018.4
Novo CY, Diermissen RH, Rojas BR. Estudio observacional en pacientes con cáncer gástrico en etapa pre y post quirúrgica desde la perspectiva fisioterapéutica, Hospital México, durante el mes Mayo 2015. Rev Med Cos Cen. 2016;73(621):765-771.
Quintero Carrión E, Nicolás Pérez D. Adenocarcinoma gástrico y de la unión esófago-gástrica. Medicine. 2004;9(2):100-11. https://doi.org/10.1016/S0211-3449(04)70235-0
Sánchez Gaitán E. Adenocarcinoma gástrico. Revista Médica Sinergia. 2017;2(1):13-21.
Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand. 1965;64:31-49. https://doi.org/10.1111/apm.1965.64.1.31
Borch K, Jonsson B, Tarpila E, Franzén T, Berglund J, Kullman E, et al. Changing pattern of histological type, location, stage and outcome of surgical treatment of gastric carcinoma. Br J Surg. 2000;87(5):618-26. https://doi.org/10.1046/j.1365-2168.2000.01425.x
Marín Martínez JD, Olarte Garzón MA, Rodríguez Lizarazo JI, Gómez Marulanda JC, Villa Molano JC, Tovar Rey MH, et al. Características de los pacientes con cáncer gástrico del departamento de Cundinamarca, remitidos al Hospital Universitario de la Samaritana entre los años 2004 y 2009. Rev Col Gastroenterol. 2010;25(4):334-48.
Quiñones J, Portanova M, Yabar A. Relación entre tipo histológico y la localización del adenocarcinoma gástrico en el Hospital Rebagliati. Rev Gastroenterol Perú. 2011;31(2):139-45.
Adrada JC, Calambás FH, Díaz JE, Delgado DO, Sierra CH. Características sociodemográficas y clínicas en una población con cáncer gástrico en el Cauca, Colombia. Rev Col Gastroenterol. 2008;23(4):309-14.
Espejo Romero H, Navarrete Siancas J. Clasificación de los adenocarcinomas de estómago. Rev Gastroenterol Perú. 2003;23(1):199-212.
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