A importância da determinação de HER2 no câncer gástrico avançado: relato de caso clínico
DOI:
https://doi.org/10.22516/25007440.503Palavras-chave:
Câncer gástrico avançado, Tratamento, Trastuzumab, HER2Resumo
O câncer gástrico avançado é uma entidade que inclui duas situações clínicas diferentes: câncergástrico doença irressecável e metastática localmente avançada, cujo tratamento padrão é a
quimioterapia. A superexpressão do receptor 2 do fator de crescimento epidérmico humano (HER2)
pode ocorrer nesta doença de 9% a 38% e tem sido o primeiro biomarcador preditivo usado para o
tratamento direcionado com trastuzumabe em pacientes com tumores gástricos e abdominais. Região
gastroesofágica avançada. Este artigo apresenta o caso de um paciente com câncer gástrico
avançado HER2-positivo tratado com quimioterapia convencional mais trastuzumabe como terapia
alvo com resposta clínica adequada.
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