Chronic Diarrhea Due to Intestinal Spirochaetosis in an HIV-Positive Patient: Case Report and Literature Review
DOI:
https://doi.org/10.22516/25007440.954Keywords:
Brachyspira, Diarrhea, Colonoscopy, SpirochaetalesAbstract
Intestinal spirochaetosis refers to the colonization of the colorectal epithelium by anaerobic spirochetes of the genus Brachyspira. It is more frequently identified in developing countries or when sanitation conditions are suboptimal. It can affect anyone, although it is more common in gay men, particularly those infected with the human immunodeficiency virus (HIV). Its most common symptom is chronic watery diarrhea. A colonoscopy may be expected. We present the clinical case of a young male patient with chronic diarrhea of several years of evolution resolved by specific treatment. In addition, a review of the literature on this disease is provided.
Downloads
References
Knox TA, Speigelman D, Skinner MA, Gorbach S. Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection. Am J Gastroenterol. 2000;95(12):3482-9. https://doi.org/10.1111/j.1572-0241.2000.03365.x
Harland WA, Lee FD. Intestinal spirochaetosis. Br Med J. 1967;3(5567):718-9. https://doi.org/10.1136/bmj.3.5567.718
Vinagre-Rodríguez G, Fernandez-Gonzalez N, Hernandez-Alonso M, Martinez Quintana E, Molina-Infante J. Espiroquetosis intestinal: una causa infrecuente de diarrea crónica. Gastroenterol Hepatol. 2015;38(8):512-3. https://doi.org/10.1016/j.gastrohep.2014.11.010
Esteve M, Salas A, Fernández-Bañares F, Lloreta J, Mariné M, Gonzalez CI, et al. Intestinal spirochetosis and chronic watery diarrhea: clinical and histological response to treatment and long-term follow up. J Gastroenterol Hepatol. 2006;21(8):1326-33. https://doi.org/10.1111/j.1440-1746.2006.04150.x
Garcia-Hernandez D, Vall-Mayans M, Coll-Estrada S, Naranjo-Hans L, Armengol P, Iglesias MA, et al. Human intestinal spirochetosis, a sexually transmissible infection? Review of six cases from two sexually transmitted infection centres in Barcelona. Int J STD AIDS. 2021;32(1):52-8. https://doi.org/10.1177/0956462420958350
Ajose TA, Aniekwena J, Effoe VS, Simien M. Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV. Case Rep Gastrointest Med. 2019;2019:1504079. https://doi.org/10.1155/2019/1504079
Ena J, Simón-Aylón A, Pasquau F. Intestinal spirochetosis as a cause of chronic diarrhoea in patients with HIV infection: case report and review of the literature. Int J STD AIDS. 2009;20(11):803-5. https://doi.org/10.1258/ijsa.2009.009177
Weisheit B, Bethke B, Stolte M. Human intestinal spirochetosis: analysis of the symptoms of 209 patients. Scand J Gastroenterol. 2007;42(12):1422-7. https://doi.org/10.1080/00365520701245629
Tateishi Y, Takahashi M, Horiguchi S, Funata N, Koizumi K, Okudela K, et al. Clinicopathologic study of intestinal spirochetosis in Japan with special reference to human immunodeficiency virus infection status and species types: analysis of 5265 consecutive colorectal biopsies. BMC Infect Dis. 2015;15:13. https://doi.org/10.1186/s12879-014-0736-4
Anthony NE, Blackwell J, Ahrens W, Lovell R, Scobey MW. Intestinal spirochetosis: an enigmatic disease. Dig Dis Sci. 2013;58(1):202-8. https://doi.org/10.1007/s10620-012-2305-2
Lozano C, Arellano L, Yaquich P. Espiroquetosis intestinal humana: serie clínica y revisión de la literatura. Rev Chilena Infectol. 2012;29(4):449-52. https://doi.org/10.4067/S0716-10182012000400015
Tsinganou E, Gebbers JO. Human intestinal spirochetosis - a review. GMS Ger Med Sci. 2010;8:Doc01. https://doi.org/10.3205/000090
Cooper C, Cotton DW, Hudson MJ, Kirkham N, Wilmott FE. Rectal spirochaetosis in homosexual men: characterisation of the organism and pathophysiology. Genitourin Med. 1986;62(1):47-52. https://doi.org/10.1136/sti.62.1.47
Alsaigh N, Fogt F. Intestinal spirochetosis: clinicopathological features with review of the literature. Colorectal Dis. 2002;4(2):97-100. https://doi.org/10.1046/j.1463-1318.2002.00284.x
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Revista colombiana de Gastroenterología

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Aquellos autores/as que tengan publicaciones con esta revista, aceptan los términos siguientes:
Los autores/as ceden sus derechos de autor y garantizarán a la revista el derecho de primera publicación de su obra, el cuál estará simultáneamente sujeto a la Licencia de reconocimiento de Creative Commons que permite a terceros compartir la obra siempre que se indique su autor y su primera publicación en esta revista.
Los contenidos están protegidos bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.

Article metrics | |
---|---|
Abstract views | |
Galley vies | |
PDF Views | |
HTML views | |
Other views |