Compromiso gastrointestinal y hepático en Síndrome de Sjögren primario: reporte de caso y revisión de la literatura
DOI:
https://doi.org/10.22516/25007440.918Keywords:
Sjögren’s syndrome, Sclerosing cholangitis, Digestive system abnormalities, Antinuclear antibodies, Gastrointestinal diseasesAbstract
Sjögren's syndrome is a systemic autoimmune disease characterized by ocular and oral dryness due to exocrine gland involvement, however, it can manifest with gastrointestinal symptoms covering a wide spectrum ranging from esophageal and intestinal dysmotility, achalasia, hypochlorhydria, chronic atrophic gastritis, to pancreatic enzymodeficiency, biliary dysfunction and liver cirrhosis, presenting variation in its clinical manifestations, and associating erroneous approaches in many occasions. This article reviews the gastrointestinal manifestations of Sjögren's syndrome, and presents the case of a woman in the eighth decade of life with Sjögren's syndrome, presenting asymptomatic at hepatobiliary level, documentation of alteration in liver profile tests, and subsequent diagnosis of primary sclerosing cholangitis, receiving initial management with ursodeoxycholic acid and retrograde cholangiopancreatography with endoscopic dilatations. This association is infrequent and warrants special consideration.
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