Hookwoorm: a little common cause of severe anemia
DOI:
https://doi.org/10.22516/25007440.250Keywords:
ancylostomiasis, anemia, iron deficiency, helminths, intestinal parasitosisAbstract
Anemia is characterized by low levels of hemoglobin. In Colombia, anemia affects 27.7% of the population. The most seriously affected populations are preschool children, women of reproductive age, pregnant women and the elderly.
Clinical case: Upon admission, the 58-year-old patient was found to have a condition compatible with cardiomegaly and redistribution of blood flow and required a blood transfusion. Additional studies suggested that digestive hemorrhaging due to ancylostomiasis could be the cause. Treatment with anthelmintics was begun and had good clinical and paraclinical results.
Discussion: Acquisition of this parasite, considered to be a forgotten cause of digestive bleeding, is associated with multiple risk factors. In some cases, there are severe consequences such as cardiomegaly and redistribution of blood flow. The effectiveness of treatment with anthelmintics ranges between 62% and 92%.
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References
Wieringa FT, Dahl M, Chamnan C, Poirot E, Kuong K, Sophonneary P, et al. The High Prevalence of Anemia in Cambodian Children and Women Cannot Be Satisfactorily Explained by Nutritional Deficiencies or Hemoglobin Disorders. Nutrients. 2016;8(6). pii: E348. https://doi.org/10.3390/nu8060348
World Health Organization (WHO). The Global Prevalence of Anemia in 2011. Génova: WHO; 2015.
Alfonso L, Arango D, Argoty D, Ramírez L, Rodríguez J. Anemia ferropénica en la población escolar de Colombia. Una revisión de la literatura. Rev Biociencias. 2017;3:1-9.
Mugisha JO, Baisley K, Asiki G, Seeley J, Kuper H. Prevalence, Types, Risk Factors and Clinical Correlates of Anaemia in Older People in a Rural Ugandan Population. PLoS ONE. 2013;8(10):78-84. https://doi.org/10.1371/journal.pone.0078394.
Lopez A, Cacoub P, Macdougall IC, Peyrin-Biroulet L. Iron deficiency anaemia. Lancet. 2015;387:907-16. https://doi.org/10.1016/S0140-6736(15)60865-0.
Ghoshal UC, Venkitaramanan A, Verma A, Misra A, Saraswat VA. Hookworm infestation is not an uncommon cause of obscure occult and overt gastrointestinal bleeding in an endemic area: A study using capsule endoscopy. Indian J Gastroenterol. 2015;34(6):463-7. https://doi.org/10.1007/s12664-015-0611-2.
Casmo V, Augusto G, Nala R, Sabonete A, Carvalho-Costa FA. The effect of hookworm infection and urinary schistosomiasis on blood hemoglobin concentration of schoolchildren living in northern Mozambique. Rev Inst Med Trop Sao Paulo. 2014;56(3):219-24. https://doi.org/10.1590/S0036-46652014000300007.
Bartsch SM, Hotez PJ, Asti L, Zapf KM, Bottazzi ME, Diemert DJ, et al. The Global Economic and Health Burden of Human Hookworm Infection. PLoS Negl Trop Dis. 2016;10(9):24-9. https://doi.org/10.1371/journal.pntd.0004922.
Alemu M, Kinfe B, Tadesse D, Mulu W, Hailu T, Yizengaw E. Intestinal parasitosis and anaemia among patients in a Health Center, North Ethiopia. BMC Res Notes. 2017;10(1):632. https://doi.org/10.1186/s13104-017-2957-2.
Degarege A, Yimam Y, Madhivanan P, Erko B. The relationship between helminth infections and low haemoglobin levels in Ethiopian children with blood type A. J Helminthol. 2017;91(3):278-283. https://doi.org/10.1017/S0022149X16000286.
Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S, et al. Hookworm infection, current concepts. N Engl J Med. 2014;351:799-807. https://doi.org/10.1056/NEJMra032492.
Srygley FD, Gerardo CJ, Tran T, Fisher DA. Does this patient have a severe upper Gastrointestinal bleed? JAMA. 2012;307:1072-9. https://doi.org/10.1001/jama.2012.253.
Liao Z, Gao R, Li F, Xu C, Zhou Y, Wang JS, et al. Fields of applications, diagnostic yields and findings of OMOM capsule endoscopy in 2400 Chinese patients. World J Gastroenterol. 2010;16:2669-76. https://doi.org/10.3748/wjg.v16.i21.2669.
Grimes JET, Tadesse G, Gardiner IA, Yard E, Wuletaw Y, Templeton MR, et al. Sanitation, hookworm, anemia, stunting, and wasting in primary school children in southern Ethiopia: Baseline results from a study in 30 schools. PLoS Negl Trop Dis. 2017;11(10):1-18. https://doi.org/10.1371/journal.pntd.0005948.
Botero D, Restrepo M. Parasitosis intestinales por helmintos. Parasitosis Humanas. 5.a edición. Medellín: Corporación de investigaciones biológicas; 2012. p. 121-214.
Cho IJ, Mun YC, Kwon KH, Shin GJ. Effect of anemia correction on left ventricular structure and fi lling pressure in anemic patients without overt heart disease. Korean J Intern Med. 2014;29(5):445-53. https://doi.org/10.3904/kjim.2014.29.4.445.
Vargas P, Hurtado R, Villalobos JA. Esplenomegalia. Rev Facul Medic UNAM. 2013;56(2):36-45.
Kassebaum NJ, Jasrasaria R, Naghavi M, Wulf SK, Johns N, Lozano R, et al. A systematic analysis of global anemia burden from 1990 to 2010. J Blood. 2014;123(5):615-24. https://doi.org/10.1182/blood-2013-06-508325.
Levecke B, Behnke JM, Ajjampur SSR, Albonico M, Ame SM, Charlier J, et al. A comparison of the sensitivity and fecal egg counts of the McMaster egg counting and Kato-Katz thick smear methods for soiltransmitted helminths. PLoS Negl Trop Dis. 2011;5:12-9. https://doi.org/10.1371/journal.pntd.0001201.
Echazua A, Juarez M, Vargas PA, Cajal SP, Cimino RO, Heredia V, et al. Albendazole and ivermectin for the control of soil-transmitted helminths in an area with high prevalence of Strongyloides stercoralis and hookworm in northwestern Argentina: A community-based pragmatic study. PLoS Negl Trop Dis. 2017;11(10):1-20. https://doi.org/10.1371/journal.pntd.0006003.
Steinmann P, Utzinger J, Du ZW, Jiang JY, Chen JX, Hattendorf J, et al. Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial. PLoS One. 2011;6(9):e25003. https://doi.org/10.1371/journal.pone.0025003.
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