Association Between Polycystic Ovary Syndrome and Fatty Liver Disease in Women: A Literature Review
DOI:
https://doi.org/10.22516/25007440.1238Keywords:
Nonalcoholic fatty liver disease, polycystic ovary syndrome, insulin resistance, Obesity Management, hyperandrogenismAbstract
Introduction: Metabolic dysfunction-associated fatty liver disease (MAFLD) is a multisystem condition with a spectrum that begins with simple steatosis, followed by nonalcoholic steatohepatitis, and may progress to fibrosis. Its prevalence among women with polycystic ovary syndrome (PCOS) ranges from 34% to 70%, a relationship explained pathophysiologically by insulin resistance, obesity, hyperandrogenism, and other contributing factors. Currently, there is no approved treatment for either condition; therefore, management should focus on lifestyle modifications, including proper nutrition, weight loss, and physical activity—either as stand-alone strategies or in combination with pharmacological therapy.
Materials and methods: This article reviews current evidence on the association between fatty liver disease and PCOS. A literature search was conducted using DeCS and MeSH terms in both Spanish and English, including studies published from 2014 to date.
Conclusion: It is recommended that all women with PCOS undergo liver function testing and imaging studies (such as ultrasound and elastography) for the diagnosis of MAFLD.
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