Jejunal Adenocarcinoma: A Report of Two Cases
DOI:
https://doi.org/10.22516/25007440.1165Keywords:
Jejunum, Adenocarcinoma, Double-Balloon Enteroscopy, Lymph Nodes, Neoplasm MetastasisAbstract
Introduction: Adenocarcinomas of the small intestine are a rare cause of gastrointestinal neoplasms. Their incidence increases with age and has recently been reported to be on the rise, likely due to the implementation of advanced diagnostic tests. Nevertheless, they remain a diagnostic challenge, leading to delayed care, especially in patients with advanced disease, which limits treatment options and worsens prognosis.
Case Report: This article presents two cases of patients diagnosed with jejunal adenocarcinoma. Both patients exhibited nonspecific symptoms and imaging and endoscopic evidence of small intestinal lesions. They were treated with minimally invasive surgery, and the diagnosis was confirmed histopathologically. The first patient experienced tumor recurrence at three years, presenting with advanced-stage disease. The second case involved hepatic and cervical lymph node metastases identified at the time of diagnosis.
Discussion and Conclusions: Despite the atypical presentation and advanced stage at diagnosis, both patients received surgical and systemic oncological treatment. However, further studies are needed to assess the potential implementation of new diagnostic and therapeutic strategies aimed at improving clinical outcomes.
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Yao H, Sokas C, Welch HG. Rising incidence of cancer of the small intestine: Overdiagnosis and better diagnosis of low-lethality disease. Gastroenterology. 2022;162(6):1749-1751.e2. https://doi.org/10.1053/j.gastro.2022.01.012
Pereira R, Tojal A, Gomes A, Casimiro C, Moreira S, Vieira F, et al. Adenocarcinoma of the jejunum: management of a rare small bowel neoplasm. J Surg Case Rep. 2021;2021(4):rjab124. Disponible en: https://doi.org/10.1093/jscr/rjab124
Li J, Wang Z, Liu N, Hao J, Xu X. Small bowel adenocarcinoma of the jejunum: a case report and literature review. World J Surg Oncol. 2016;14(1):177. https://doi.org/10.1186/s12957-016-0932-3
Galindo F, Lencinas S. Tumores del intestino delgado. Cirugía Digestiva. 2009;261:1-17.
Petreshock EP, Pessah M, Menachemi E. Adenocarcinoma of the jejunum associated with nontropical sprue. Digest Dis Sci. 1975;20(8):796-802. https://doi.org/10.1007/bf01070840
Overman MJ, Hu CY, Wolff RA, Chang GJ. Prognostic value of lymph node evaluation in small bowel adenocarcinoma: Analysis of the surveillance, epidemiology, and end results database. Cancer. 2010;116(23):5374-82. https://doi.org/10.1002/cncr.25324
Overman MJ, Hu C-Y, Kopetz S, Abbruzzese JL, Wolff RA, Chang GJ, et al. A population-based comparison of adenocarcinoma of the large and small intestine: Insights into a rare disease. Ann Surg Oncol. 2012;19(5):1439-45. Disponible en: https://doi.org/10.1245/s10434-011-2173-6
Chen E, Vaccaro G. Small bowel adenocarcinoma. Clin Colon Rectal Surg. 2018;31(05):267-77. https://doi.org/10.1055/s-0038-1660482
Williamson RCN, Welch CE, Malt RA. Adenocarcinoma and lymphoma of the small intestine: Distribution and etiologic associations. Ann Surg. 1983;197(2):172-8. https://doi.org/10.1097/00000658-198302000-00008
Pinocy J, Klotz M, Weinzierl B, Schunck R, Weber P. Primäres Adenokarzinom des Dünndarms. Dtsch Med Wochenschr. 2008;133(20):1064-7. https://doi.org/10.1055/s-2008-1077218
Umman P, Adiyodi V, Narayan C. Small bowel adenocarcinoma – report of two cases and review of literature. Indian J Surg. 2013;75(2):123-7. https://doi.org/10.1007/s12262-012-0598-1
Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J. Adenocarcinoma of the small bowel: Presentation, prognostic factors, and outcome of 217 patients. Cancer. 2004;101(3):518-26. https://doi.org/10.1002/cncr.20404
Lee HJ, Cha JM, Lee JI, Joo KR, Jung SW, Shin HP, et al. A case of jejunal adenocarcinoma diagnosed by preoperative double balloon enteroscopy. Gut Liver. 2009;3(4):311-4. https://doi.org/10.5009/gnl.2009.3.4.311
Neishaboori H, Fakheri H, Emadian O, Ebrahimipakzad SH, Firoozi MS. Primary adenocarcinoma of jejunum: A case report. J Gastrointest Cancer. 2014;45(S1):58-61. https://doi.org/10.1007/s12029-013-9536-0
Kusunoki N, Shimada Y, Fukumoto S, Iwatani Y, Ohshima T, Arahi E, et al. Adenocarcinoma arising in a tubular duplication of the jejunum. J Gastroenterol. 2003;38(8):781-5. https://doi.org/10.1007/s00535-002-1146-8
Barwood N, Platell C. Case report: Adenocarcinoma arising in a Crohn’s stricture of the jejunum. J Gastroenterol Hepatol. 1999;14(11):1132-4. https://doi.org/10.1046/j.1440-1746.1999.02020.x
Caruso ML, Marzullo F. Jejunal adenocarcinoma in congenital heterotopic gastric mucosa. J Clin Gastroenterol. 1988;10(1):92-4. https://doi.org/10.1097/00004836-198802000-00020

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