Melanoma anorrectal primario: reporte de un caso y revisión de una neoplasia infrecuente
DOI:
https://doi.org/10.22516/25007440.993Palabras clave:
Melanoma Maligno, Neoplasias del Ano, Neoplasias del Recto, Hemorragia Gastrointestinal, ColonoscopiaResumen
El melanoma anorrectal primario es una neoplasia melanocítica maligna poco frecuente, su principal manifestación es el sangrado rectal. Tiene un pronóstico ominoso con una tasa de sobrevida del 10% a 5 años. Se presenta el caso de una mujer de 56 años con rectorragia y sensación de masa rectal. Durante la colonoscopia se documentó una lesión polipoide en el recto distal, que se resecó por vía transanal. El estudio histológico confirmó la presencia de un melanoma anorrectal primario.
Descargas
Referencias bibliográficas
Hicks CW, Pappou EP, Magruder JT, Gazer B, Fang S, Wick EC, et al. Clinicopathologic presentation and natural history of anorectal melanoma: a case series of 18 patients. JAMA Surg. 2014;149(6):608-611. https://doi.org/10.1001/jamasurg.2013.4643
Callahan A, Anderson WF, Patel S, Barnholtz-Sloan JS, Bordeaux JS, Tucker MA, et al. Epidemiology of anorectal melanoma in the United States: 1992 to 2011. Dermatol Surg. 2016;42(1):94-9. https://doi.org/10.1097/DSS.0000000000000579
Seetharamu N, Ott PA, Pavlick AC. Mucosal melanomas: a review of the literature. Oncologist. 2010;15(7):772-781. https://doi.org/10.1634/theoncologist.2010-0067
Edelman A, Brown T, Gandhi R, Gandhi R. Anorectal Melanoma Misdiagnosed as Hemorrhoids: A Case Report and Review of the Literature. J Clin Aesthet Dermatol. 2021;14(4):32-35.
Parra RS, Almeida AL, Badiale BG, Moraes MM, Rocha JJ, Féres O. Melanoma of the anal canal. Clinics (Sao Paulo). 2010;65(10):1063-65. https://doi.org/10.1590/S1807-59322010001000026
Micu E, Juzeniene A, Moan J. Comparison of the time and latitude trends of melanoma incidence in anorectal region and perianal skin with those of cutaneous malignant melanoma in Norway. J Eur Acad Dermatol Venereol. 2011;25(12):1444-9. https://doi.org/10.1111/j.1468-3083.2011.04023.x
Ragnarsson-Olding BK, Nilsson PJ, Olding LB, Nilsson BR. Primary ano-rectal malignant melanomas within a population-based national patient series in Sweden during 40 years. Acta Oncol. 2009;48(1):125-31. https://doi.org/10.1080/02841860802120861
Miller BJ, Rutherford LF, McLeod GR, Cohen JR. Where the sun never shines: Anorectal melanoma. Aust N Z J Surg. 1997;67(12):846-8. https://doi.org/10.1111/j.1445-2197.1997.tb07609.x
Postow MA, Hamid O, Carvajal RD. Mucosal melanoma: Pathogenesis, clinical behavior, and management. Curr Oncol Rep. 2012;14(5):441-8. https://doi.org/10.1007/s11912-012-0244-x
Cagir B, Whiteford MH, Topham A, Rakinic J, Fry RD. Changing epidemiology of anorectal melanoma. Dis Colon Rectum. 1999;42(9):1203-08. https://doi.org/10.1007/BF02238576
Row D, Weiser MR. Anorectal melanoma. Clin Colon Rectal Surg. 2009;22(2):120-6. https://doi.org/10.1055/s-0029-1223844
Zecca L, Zucca FA, Wilms H, Sulzer D. Neuromelanin of the substantia nigra: A neuronal black hole with protective and toxic characteristics. Trends Neurosci. 2003;26(11):578-80. https://doi.org/10.1016/j.tins.2003.08.009
Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005;353(20):2135-47. https://doi.org/10.1056/NEJMoa050092
Jensen C, Kin C. Black is the new black: Prolapsing primary anorectal melanoma. Dig Dis Sci. 2017;62(11):2991-3. https://doi.org/10.1007/s10620-017-4527-9
Smith MA, Fine JA, Barnhill RL, Berwick M. Hormonal and reproductive influences and risk of melanoma in women. Int J Epidemiol. 1998;27(5):751-7. https://doi.org/10.1093/ije/27.5.751
Bullard KM, Tuttle TM, Rothenberger DA, Madoff RD, Baxter NN, Finne CO, et al. Surgical therapy for anorectal melanoma. J Am Coll Surg. 2003;196(2):206-11. https://doi.org/10.1016/S1072-7515(02)01538-7
Smith HG, Glen J, Turnbull N, Peach H, Board R, Payne M, et al. Less is more: A systematic review and meta-analysis of the outcomes of radical versus conservative primary resection in anorectal melanoma. Eur J Cancer. 2020;135:113-120. https://doi.org/10.1016/j.ejca.2020.04.041
Pessaux P, Pocard M, Elias D, Duvillard P, Avril MF, Zimmerman P, et al. Surgical management of primary anorectal melanoma. Br J Surg. 2004;91(9):1183-7. https://doi.org/10.1002/bjs.4592
Nam S, Kim CW, Baek SJ, Hur H, Min BS, Baik SH, et al. The clinical features and optimal treatment of anorectal malignant melanoma. Ann Surg Treat Res. 2014;87(3):113-17. https://doi.org/10.4174/astr.2014.87.3.113
Zhou HT, Zhou ZX, Zhang HZ, Bi JJ, Zhao P. Wide local excision could be considered as the initial treatment of primary anorectal malignant melanoma. Chin Med J (Engl). 2010;123(5):585-8.
David AW, Perakath B. Management of anorectal melanomas: a 10-year review. Trop Gastroenterol. 2007;28(2):76-8.
Slingluff CL Jr, Vollmer RT, Seigler HF. Anorectal melanoma: clinical characteristics and results of surgical management in twenty-four patients. Surgery. 1990;107(1):1-9.
Das G, Gupta S, Shukla PJ, Jagannath P. Anorectal melanoma: a large clinicopathologic study from India. Int Surg. 2003;88(1):21-4.
Chae WY, Lee JL, Cho D-H, Yu SK, Roh, J, Kim JC. Preliminary suggestion about staging of anorectal malignant melanoma may be used to predict prognosis. Cancer Res Treat. 2016;48(1):240-9. https://doi.org/10.4143/crt.2014.305
Podnos YD, Tsai NC, Smith D, Ellenhorn JD. Factors affecting survival in patients with anal melanoma. Am Surg. 2006;72(10):917-20. https://doi.org/10.1177/000313480607201017
Yeh JJ, Shia J, Hwu WJ, Busam KJ, Paty PB, Guillem JG, et al. The role of abdominoperineal resection as surgical therapy for anorectal melanoma. Ann Surg. 2006;244(6):1012-17. https://doi.org/10.1097/01.sla.0000225114.56565.f9
Falch C, Mueller S, Kirschniak A, Braun M, Koenigsrainer A, Klumpp B. Anorectal malignant melanoma: Curative abdominoperineal resection: patient selection with 18F-FDG-PET/CT. World J Surg Oncol. 2016;14(1):185. https://doi.org/10.1186/s12957-016-0938-x
Ceccopieri B, Marcomin AR, Vitagliano F. Primary anorectal malignant melanoma: report of two cases. Tumori. 2000;86(4):356-8. https://doi.org/10.1177/030089160008600430
Bujko K, Nowacki MP, Liszka-Deleck P. Radiation therapy for anorectal melanoma - a report of three cases. Acta Oncol. 1998;37(5):497-9. https://doi.org/10.1080/028418698430485
Moozar KL, Wong CS, Couture J. Anorectal malignant melanoma: treatment with surgery or radiation therapy, or both. Can J Surg. 2003;46(5):345-9.
Tacastacas JD, Bray J, Cohen YK, Arbesman J, Kim J, Koon HB, et al. Update on primary mucosal melanoma. J Am Acad Dermatol. 2014;71(2):366-753. https://doi.org/10.1016/j.jaad.2014.03.031
Chapman PB, Einhorn LH, Meyers ML, Saxman S, Destro AN, Panageas KS, et al. Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. J Clin Oncol. 1999;17(9):2745-51. https://doi.org/10.1200/JCO.1999.17.9.2745
Singhal NK, Ostwal VS, Shrikhande SV, Saklani A, Arya S, Ramadvar M. Systemic therapy in anorectal melanoma: Does choice of systemic therapy matter? ASCO. J Clin Oncol. 2016;34(suppl 4S; abstr 731). https://doi.org/10.1200/jco.2016.34.4_suppl.731
Thibault C, Sagar P, Nivatvongs S, Ilstrup DM, Wolff BG. Anorectal melanoma--an incurable disease? Dis Colon Rectum. 1997;40(6):661-8. https://doi.org/10.1007/BF02140894
Shoushtari AN, Bluth MJ, Goldman DA, Bitas C, Lefkowitz RA, Postow MA, et al. Clinical features and response to systemic therapy in a historical cohort of advanced or unresectable mucosal melanoma. Melanoma Res. 2017;27(1):57-64. https://doi.org/10.1097/CMR.0000000000000306
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2023 Revista colombiana de Gastroenterología
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.
Aquellos autores/as que tengan publicaciones con esta revista, aceptan los términos siguientes:
Los autores/as ceden sus derechos de autor y garantizarán a la revista el derecho de primera publicación de su obra, el cuál estará simultáneamente sujeto a la Licencia de reconocimiento de Creative Commons que permite a terceros compartir la obra siempre que se indique su autor y su primera publicación en esta revista.
Los contenidos están protegidos bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.
| Estadísticas de artículo | |
|---|---|
| Vistas de resúmenes | |
| Vistas de PDF | |
| Descargas de PDF | |
| Vistas de HTML | |
| Otras vistas | |
