Síndromes paraneoplásicos en tumores gastrointestinales. Revisión de tema
DOI:
https://doi.org/10.22516/25007440.155Palabras clave:
síndrome paraneoplásico, gastrointestinal, tumoresResumen
Los síndromes paraneoplásicos representan manifestaciones clínicas que producen los tumores en sitios distantes a ellos y que no están relacionadas físicamente con ellos ni con sus metástasis. Diferentes tumores gastrointestinales pueden presentar síndromes o manifestaciones sistémicas, dermatológicas, hematológicas, renales y neurológicas entre otras. Aquí se ofrece una revisión de esas distintas manifestacionesDescargas
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esReferencias bibliográficas
Kanaji N, Watanabe N, Kita N, Bandoh S, Tadokoro A, Ishii T, et al. Paraneoplastic syndromes associated with lung cancer. World J Clin Oncol. 2014;5(3):197-223.
https://doi.org/10.5306/wjco.v5.i3.197
Jameson JL, Longo DL. Paraneoplastic syndromes: endocrinologic/hematologic. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, editors. Harrison's principles of internal medicine, 19e. New York: McGraw-Hill Education; 2015.
Pelosof LC, Gerber DE. Paraneoplastic syndromes: an approach to diagnosis and treatment. Mayo Clin Proc 2010;85(9):838-54.
https://doi.org/10.4065/mcp.2010.0099
Darnell RB, Posner JB. Paraneoplastic syndromes involving the nervous system. The New England journal of medicine. 2003;349(16):1543-54.
https://doi.org/10.1056/NEJMra023009
Cambier JF, Ronco P. Onco-nephrology: glomerular diseases with cancer. Clin J Am Soc Nephrol 2012;7(10):1701-12.
https://doi.org/10.2215/CJN.03770412
Aoyagi T, Terracina KP, Raza A, Matsubara H, Takabe K. Cancer cachexia, mechanism and treatment. World J Gastrointest Oncol 2015;7(4):17-29.
Tsoli M, Robertson G. Cancer cachexia: malignant inflammation, tumorkines, and metabolic mayhem. Tren Endocr Met. 2013;24(4):174-83.
https://doi.org/10.1016/j.tem.2012.10.006
Nicolini A, Ferrari P, Masoni MC, Fini M, Pagani S, Giampietro O, et al. Malnutrition, anorexia and cachexia in cancer patients: a mini-review on pathogenesis and treatment. Biomed Pharmac. 2013;67(8):807-17.
https://doi.org/10.1016/j.biopha.2013.08.005
Petruzzelli M, Schweiger M, Schreiber R, Campos-Olivas R, Tsoli M, Allen J, et al. A switch from white to brown fat increases energy expenditure in cancer-associated cachexia. Cell Metab. 2014;20(3):433-47.
https://doi.org/10.1016/j.cmet.2014.06.011
Al-Zoughbi W, Huang J, Paramasivan GS, Till H, Pichler M, Guertl-Lackner B, et al. Tumor macroenvironment and metabolism. Sem Oncol 2014;41(2):281-95.
https://doi.org/10.1053/j.seminoncol.2014.02.005
Morley JE, Farr SA. Cachexia and neuropeptide Y. Nutrition. 2008;24(9):815-9.
https://doi.org/10.1016/j.nut.2008.06.020
Richards CH, Roxburgh CSD, MacMillan MT, Isswiasi S, Robertson EG, Guthrie GK, et al. The Relationships between body composition and the systemic inflammatory response in patients with primary operable colorectal cancer. PLoS ONE. 2012;7(8):e41883.
https://doi.org/10.1371/journal.pone.0041883
Silva JA, Mesquita Kde C, Igreja AC, Lucas IC, Freitas AF, Oliveira SM, et al. Paraneoplastic cutaneous manifestations: concepts and updates. Anais Brasileiros de Dermatologia. 2013;88(1):9-22.
https://doi.org/10.1590/S0365-05962013000100001
Dourmishev LA, Draganov PV. Paraneoplastic dermatological manifestation of gastrointestinal malignancies. World J Gastroenterol. 2009;15(35):4372-9.
https://doi.org/10.3748/wjg.15.4372
Shah KR, Boland CR, Patel M, Thrash B, Menter A. Cutaneous manifestations of gastrointestinal disease: part I. J Am Acad Dermatol. 2013;68(2):189.e1-21.
https://doi.org/10.1016/j.jaad.2012.10.037
Phiske MM. An approach to acanthosis nigricans. Indian Dermatology Online Journal. 2014;5(3):239-49.
https://doi.org/10.4103/2229-5178.137765
Faizal M. Manifestaciones cutáneas de neoplasias extracutaneas y paraneoplasias. En : Cáncer de la piel. Bogotá: Universidad Nacional de Colombia; 2014. 385-546.
Woo VL, Abdelsayed R. Oral manifestations of internal malignancy and paraneoplastic syndromes. Dent Clin North Am. 2008;52(1):203-30.
https://doi.org/10.1016/j.cden.2007.09.005
Yosipovitch G. Chronic pruritus: a paraneoplastic sign. Dermatol Ther. 2010;23(6):590-6.
https://doi.org/10.1111/j.1529-8019.2010.01366.x
Yang YH, Zhang RZ, Kang DH, Zhu WY. Three paraneoplastic signs in the same patient with gastric adenocarcinoma. Dermatol Online Journal. 2013;19(7):15.
Stawczyk-Macieja M, Szczerkowska-Dobosz A, Nowicki R, Majewska H, Dubowik M, Sokołowska-Wojdyło M. Malignant acanthosis nigricans, florid cutaneous papillomatosis and tripe palms syndrome associated with gastric adenocarcinoma. Postȩpy Dermatologii I Alergologii. 2014;31(1):56-8.
https://doi.org/10.5114/pdia.2014.40663
Krawczyk M, Mykała-Cieśla J, Kołodziej-Jaskuła A. Acanthosis nigricans as a paraneoplastic syndrome. Case reports and review of literature. Polskie Archiwum Medycyny Wewnętrznej. 2009;119(3):180-3.
Zhang N, Qian Y, Feng AP. Acanthosis nigricans, tripe palms, and sign of Leser-Trélat in a patient with gastric adenocarcinoma: case report and literature review in China. Int J Dermatol 2015;54(3):338-42.
https://doi.org/10.1111/ijd.12034
Ponti G, Luppi G, Losi L, Giannetti A, Seidenari S. Leser-Trelat syndrome in patients affected by six multiple metachronous primitive cancers. J Hematol Oncol 2010;3:2.
https://doi.org/10.1186/1756-8722-3-2
Ramos-e-Silva M, Carvalho JC, Carneiro SC. Cutaneous paraneoplasia. Clin Dermatol. 2011;29(5):541-7.
https://doi.org/10.1016/j.clindermatol.2010.09.022
Nanda A, Mamon HJ, Fuchs CS. Sign of Leser-Trelat in newly diagnosed advanced gastric adenocarcinoma. J Clin Oncol 2008;26(30):4992-3.
https://doi.org/10.1200/JCO.2008.17.9143
Medenica L, Gajic-Veljic M, Skiljevic D, Pesko P. Acrokeratosis paraneoplastica Bazex syndrome associated with esophageal squamocellular carcinoma. Vojnosanitetski pregled. 2008;65(6):485-7.
https://doi.org/10.2298/VSP0806485M
Poligone B, Christensen SR, Lazova R, Heald PW. Bazex syndrome (acrokeratosis paraneoplastica). Lancet. 2007;369(9560):530.
https://doi.org/10.1016/S0140-6736(07)60240-2
Rao R, Shenoi SD. Acrokeratosis paraneoplastica (Bazex syndrome): an atypical presentation. Dermatology Online Journal. 2004;10(1):21.
Rodrigues IA, Jr., Gresta LT, Cruz RC, Carvalho GG, Moreira MH. Bazex syndrome. Anais Brasileiros de Bermatologia. 2013;88(6 Suppl 1):209-11.
https://doi.org/10.1590/abd1806-4841.20132488
Mirowski GW, Leblanc J, Mark LA. Oral disease and oral-cutaneous manifestations of gastrointestinal and liver disease. In: Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and fordtran's gastrointestinal and liver disease: Pathophysiology, diagnosis, management. 10 ed. United States: Elsevier; 2016: 377-96e2.
Saad N, Hot A, Ninet J, Claudy A, Faure M. Acquired hypertrichosis lanuginosa and gastric adenocarcinoma. Annales de Dermatologie et de Venereologie. 2007;134(1):55-8.
https://doi.org/10.1016/S0151-9638(07)88991-5
Lee SE, Kim S-C. Paraneoplastic pemphigus. Dermatologica Sinica. 2010;28(1):1-14.
https://doi.org/10.1016/S1027-8117(10)60001-8
Espinoza-Cobos JC, Perez-Figueroa J, Zuniga-Ahuet G, Dorantes MA, Grube-Pagola P, Ruiz-Juarez I, et al. Oropharyngeal dysphagia as a first manifestation of dermatomyositis associated with colon cancer. Rev Gastroenterol Mex. 2010;75(4):522-7.
Martel S, De Angelis F, Lapointe E, Larue S, Speranza G. Paraneoplastic neurologic syndromes: clinical presentation and management. Curr Prob Cancer. 2014;38(4):115-34.
https://doi.org/10.1016/j.currproblcancer.2014.08.002
Femia AN, Vleugels RA, Callen JP. Cutaneous dermatomyositis: an updated review of treatment options and internal associations. Am J Clin Dermatol. 2013;14(4):291-313.
https://doi.org/10.1007/s40257-013-0028-6
Mayet WJ. Gastrointestinal tumors. Clinical manifestations of paraneoplastic rheumatic symptoms]. Zeitschrift für Rheumatologie. 2011;70(7):567-72.
https://doi.org/10.1007/s00393-011-0812-8
Voltz R. Paraneoplastic neurological syndromes: an update on diagnosis, pathogenesis, and therapy. Lancet Neurol. 2002;1(5):294-305.
https://doi.org/10.1016/S1474-4422(02)00135-7
Leypoldt F, Wandinger KP. Paraneoplastic neurological syndromes. Clin Exper Immunol 2014;175(3):336-48.
https://doi.org/10.1111/cei.12185
Terada T. Signet-ring cell carcinoma of the esophagus in dermatomyositis: a case report with immunohistochemical study. J Gastrointest Cancer. 2013;44(4):489-90.
https://doi.org/10.1007/s12029-012-9469-z
https://doi.org/10.1007/s12029-012-9473-3
Harrison BA, Heck SI, Hood AF. A fatal case of dermatomyositis with underlying metastatic esophageal adenocarcinoma. Cutis. 2008;81(1):26-8.
Di Rollo D, Abeni D, Tracanna M, Capo A, Amerio P. Cancer risk in dermatomyositis: a systematic review of the literature. Giornale Italiano di Dermatologia e Venereologia : organo ufficiale, Società Italiana di Dermatologia e Sifilografia. 2014;149(5):525-37.
Lefkowitz EG, Natow AJ. Pityriasis Rotunda: A Case Report of Familial Disease in an American-Born Black Patient. Case Reports in Dermatology. 2016;8(1):71-74.
https://doi.org/10.1159/000445043
Kovacova E, Kinova S, Duris I, Remkova A. General changes in hemostasis in gastric cancer. Bratislavske Lekarske Listy. 2009;110(4):215-21.
Caine GJ, Stonelake PS, Lip GYH, Kehoe ST. The Hypercoagulable state of malignancy: pathogenesis and current debate. Neoplasia. 2002;4(6):465-73.
https://doi.org/10.1038/sj.neo.7900263
Chung W-S, Lin C-L, Hsu W-H, Sung F-C, Li R-Y, Kao C-H. Idiopathic venous thromboembolism: a potential surrogate for occult cancer. 2014; 107(7):529-36.
Monreal M, Trujillo-Santos J. Screening for occult cancer in patients with acute venous thromboembolism. Curr Opin Pulmon Med. 2007;13(5):368-71.
https://doi.org/10.1097/MCP.0b013e3282058b6f
Timp JF, Braekkan SK, Versteeg HH, Cannegieter SC. Epidemiology of cancer-associated venous thrombosis. Blood. 2013;122(10):1712-23.
https://doi.org/10.1182/blood-2013-04-460121
M Di Nisio, Otten HM, Piccioli A, Lensing AW, Prandoni P, Buller HR, et al. Decision analysis for cancer screening in idiopathic venous thromboembolism. J Thromb Haem. 2005;3(11):2391-6.
https://doi.org/10.1111/j.1538-7836.2005.01606.x
Thrumurthy SG, Anuruddha AH, De Zoysa MI, Samarasekera DN. Unexpected outcome from Trousseau syndrome. BMC Surgery. 2011;11:1.
https://doi.org/10.1186/1471-2482-11-1
Sierra-Montenegro E, Sierra-Luzuriaga G, Calle-Loffredo D, Rodríguez Quinde M. Rectal cancer and Trousseau syndrome. Case report. Cirugia y Cirujanos. 2013;81(3):242-5.
Puthenparambil J, Lechner K, Kornek G. Autoimmune hemolytic anemia as a paraneoplastic phenomenon in solid tumors: A critical analysis of 52 cases reported in the literature. Wiener Klinische Wochenschrift. 2010;122(7-8):229-36.
https://doi.org/10.1007/s00508-010-1319-z
Ahmadinejad M, Roushan N. Acquired factor V inhibitor developing in a patient with esophageal squamous cell carcinoma. Blood Coag Fibrin 2013;24(1):97-9.
https://doi.org/10.1097/MBC.0b013e328359bc59
Callacondo D, Ganoza-Salas A, Anicama-Lima W, Quispe-Mauricio A, Longacre TA. Primary squamous cell carcinoma of the stomach with paraneoplastic leukocytosis: a case report and review of literature. Hum Pathol. 2009;40(10):1494-8.
https://doi.org/10.1016/j.humpath.2009.02.014
Chakraborty S, Keenportz B, Woodward S, Anderson J, Colan D. Paraneoplastic leukemoid reaction in solid tumors. Am J Clin Oncol. 2015;38(3):326-30.
https://doi.org/10.1097/COC.0b013e3182a530dd
Takane K, Midorikawa Y, Yamazaki S, Kajiwara T, Yoshida N, Kusumi Y, et al. Gastrointestinal stromal tumor with nephrotic syndrome as a paraneoplastic syndrome: a case report. J Med Case Rep 2014;8:108-13.
https://doi.org/10.1186/1752-1947-8-108
Alpers CE, Cotran RS. Neoplasia and glomerular injury. Kidney Intern. 1986;30(4):465-73.
https://doi.org/10.1038/ki.1986.209
Bacchetta J, Juillard L, Cochat P, Droz JP. Paraneoplastic glomerular diseases and malignancies. Crit Rev Oncol/Hematol. 2009;70(1):39-58.
https://doi.org/10.1016/j.critrevonc.2008.08.003
Sawyer N, Wadsworth J, Wijnen M, Gabriel R. Prevalence, concentration, and prognostic importance of proteinuria in patients with malignancies. Br Med J 1988;296(6632):1295-8.
https://doi.org/10.1136/bmj.296.6632.1295
Kocyigit I, Dortdudak S, Eroglu E, Unal A, Sipahioglu MH, Berk V, et al. Immunoglobulin A nephropathy could be a clue for the recurrence of gastric adenocarcinoma. Nefrología: publicación oficial de la Sociedad Espanola Nefrología. 2013;33(6):853-5.
Lien YH, Lai LW. Pathogenesis, diagnosis and management of paraneoplastic glomerulonephritis. Nat Rev Nephrol. 2011;7(2):85-95.
https://doi.org/10.1038/nrneph.2010.171
Rosner MH, Dalkin AC. Electrolyte disorders associated with cancer. Adv Chr Kidney Dis. 21(1):7-17.
Yeung S, Gagel R. Endocrine paraneoplastic syndromes ("ectopic" hormone production). In: Kufe D, Pollock R, Weichselbaum R, editors. Holland-frei cancer medicine. 6th ed. 2003.
Hwang K, Jeon DH, Jang HN, Bae EJ, Lee JS, Cho HS, et al. Inappropriate antidiuretic hormone syndrome presenting as ectopic antidiuretic hormone-secreting gastric adenocarcinoma: a case report. J Med Case Rep. 2014;8:185.
https://doi.org/10.1186/1752-1947-8-185
Ando T, Hosokawa A, Yamawaki H, Hasumoto Y, Kajiura S, Itaya Y, et al. Esophageal small-cell carcinoma with syndrome of inappropriate secretion of antidiuretic hormone. Internal medicine (Tokyo, Japan). 2011;50(10):1099-103.
https://doi.org/10.2169/internalmedicine.50.4694
Murakami S, Togo S, Yasuda S, Saito M, Mishima Y. The syndrome of inappropriate secretion of antidiuretic hormone by rectal cancer.A case report. Jap J Surg. 1987;17(4):293-6.
https://doi.org/10.1007/BF02470703
Stewart AF. Clinical practice. Hypercalcemia associated with cancer. The New Engl J Med. 2005;352(4):373-9.
https://doi.org/10.1056/NEJMcp042806
Nakajima N, Ueda M, Nagayama H, Yamazaki M, Katayama Y. Posterior reversible encephalopathy syndrome due to hypercalcemia associated with parathyroid hormone-related peptide: a case report and review of the literature. Internal Medicine. 2013;52(21):2465-8.
https://doi.org/10.2169/internalmedicine.52.0444
Baas JM, Kapiteijn E, Pereira AM, Nortier JW. Atypical Cushing's syndrome caused by ectopic ACTH secretion of an oesophageal adenocarcinoma. The Netherlands Journal of Medicine. 2010;68(6):265-7.
Witek P, Witek J, Zielinski G, Podgajny Z, Kaminski G. Ectopic Cushing's syndrome in light of modern diagnostic techniques and treatment options. Neuro Endocrinology Letters. 2015;36(3):201-8.
Jensen RT, Norton JA, Oberg K. Neuroendocrine Tumors. In: Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and fordtran's gastrointestinal and liver disease: Pathophysiology, diagnosis, management. 10 ed. United States: Elsevier; 2016: 501-41.
Iglesias P, Diez JJ. Management of endocrine disease: a clinical update on tumor-induced hypoglycemia. European Journal of Endocrinology/European Federation of Endocrine Societies. 2014;170(4):R147-57.
Bojinca V, Janta I. Rheumatic diseases and malignancies. Maedica. 2012;7(4):364-71.
Nagasawa K. Rheumatic manifestations in paraneoplastic syndrome. Internal Medicine (Tokyo, Japan). 2000;39(9):685-6.
https://doi.org/10.2169/internalmedicine.39.685
Nuno Mateo FJ, Noval Menéndez J, Campoamor Serrano MT, Miranda Martínez E. Forty-eight year oldmale with dysphagia, general syndrome and finger clubbing. Revista Clínica Espanola. 2003;203(2):95-6.
Silva L, Andreu JL, Munoz P, Isasi C, López A. Hypertrophic osteoarthropathy associated with gastrointestinal stromal tumour. Annals of the Rheumatic Diseases. 2006;65(5):681-2.
https://doi.org/10.1136/ard.2005.044859
Manger B, Lindner A, Manger K, Wacker J, Schett G. Hypertrophic osteoarthropathy. Bamberger-Marie disease. Zeitschrift für Rheumatologie. 2011;70(7):554-60.
https://doi.org/10.1007/s00393-011-0813-7
Storstein A, Vedeler CA. Paraneoplastic neurological syndromes. Tidsskrift for den Norske Laegeforening: tidsskrift for praktisk medicin, ny raekke. 2009;129(6):524-8.
https://doi.org/10.4045/tidsskr.09.35653
Foxx-Ornestein AE. Ileus and pseudo-obstruction. In: Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and fordtran's gastrointestinal and liver disease: Pathophysiology, diagnosis, management. 1n ed. United States: Elsevier; 2016: 2171-95e6.
Figueroa M, Guo Y, Tselis A, Pittock SJ, Lennon VA, Lucchinetti CF, et al. Paraneoplastic neuromyelitis optica spectrum disorder associated with metastatic carcinoid expressing aquaporin-4. JAMA Neurology. 2014;71(4):495-8.
https://doi.org/10.1001/jamaneurol.2013.6331
Al-Harbi T, Al-Sarawi A, Binfalah M, Dermime S. Paraneoplastic neuromyelitis optica spectrum disorder associated with stomach carcinoid tumor. Hematology/Oncology and Stem Cell Therapy. 2014;7(3):116-9.
https://doi.org/10.1016/j.hemonc.2014.06.001
Ogra S, Sharp D, Danesh-Meyer H. Autoimmune retinopathy associated with carcinoid tumour of the small bowel. Journal of Clinical Neuroscience: official journal of the Neurosurgical Society of Australasia. 2014;21(2):358-60.
https://doi.org/10.1016/j.jocn.2013.07.002
Boch M, Rinke A, Rexin P, Seipelt M, Brodje D, Schober M, et al. Paraneoplastic brainstem encephalitis in a patient with exceptionally long course of a metastasized neuroendocrine rectum neoplasm. BMC Cancer. 2014;14:691-5.
https://doi.org/10.1186/1471-2407-14-691
Xia K, Saltzman JR, Carr-Locke DL. Anti-Yo antibody-mediated paraneoplastic cerebellar degeneration in a man with esophageal adenocarcinoma. Med Gen Med. 2003;5(3):18.
Debes JD, Lagarde SM, Hulsenboom E, Sillevis Smitt PA, ten Kate FJ, Sulter GA, et al. Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with adenocarcinoma of the gastroesophageal junction. Digestive Surgery. 2007;24(5):395-7.
https://doi.org/10.1159/000107782
Nomani AZ, Wazir M, Kashmir SB, Qureshi MS. Diffuse large B-cell lymphoma of stomach presenting with paraneoplastic cerebellar degeneration syndrome. Journal of the College of Physicians and Surgeons-Pakistan. 2014;24 (Suppl 1):S11-3.
Lakshmaiah KC, Viveka BK, Anil Kumar N, Saini ML, Sinha S, Saini KS. Gastric diffuse large B cell lymphoma presenting as paraneoplastic cerebellar degeneration: case report and review of literature. J Egyp Nat Cancer Inst. 2013;25(4):231-5.
https://doi.org/10.1016/j.jnci.2013.07.001
Mundiyanapurath S, Jarius S, Probst C, Stöcker W, Wildemann B, Bösel J. GABA-B-receptor antibodies in paraneoplastic brainstem encephalitis. Journal of Neuroimmunology. 2013;259(1–2):88-91.
https://doi.org/10.1016/j.jneuroim.2013.04.004
Shirafuji T, Kanda F, Sekiguchi K, Higuchi M, Yokozaki H, Tanaka K, et al. Anti-Hu-associated paraneoplastic encephalomyelitis with esophageal small cell carcinoma. Internal Medicine. 2012;51(17):2423-7.
https://doi.org/10.2169/internalmedicine.51.6884
Gultekin SH, Rosenfeld MR, Voltz R, Eichen J, Posner JB, Dalmau J. Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients. Brain. 2000;123(7):1481-94.
https://doi.org/10.1093/brain/123.7.1481
Menezes RB, de Lucena AF, Maia FM, Marinho AR. Limbic encephalitis as the presenting symptom of oesophageal adenocarcinoma: another cancer to search? BMJ Case Reports 2013.
https://doi.org/10.1136/bcr-2012-008201
Aggarwal I, Beller J, Tzimas D. A case of confusion. Gastroenterology. 2014;147(6):e5-6.
https://doi.org/10.1053/j.gastro.2014.06.036
Sio TT, Paredes M, Uzair C. Neurological manifestation of colonic adenocarcinoma. Rare Tumors. 2012;4(2):98-100.
https://doi.org/10.4081/rt.2012.e32
Rossor AM, Perry F, Botha A, Norwood F. Opsoclonus myoclonus syndrome due to squamous cell carcinoma of the oesophagus. BMJ Case Reports. 2014.
https://doi.org/10.1136/bcr-2013-202849
Bataller L, Graus F, Saiz A, Vilchez JJ. Clinical outcome in adult onset idiopathic or paraneoplastic opsoclonus-myoclonus. Brain. 2001;124(Pt 2):437-43.
https://doi.org/10.1093/brain/124.2.437
Chao D, Chen W-C, Thirkill CE, Lee AG. Paraneoplastic optic neuropathy and retinopathy associated with colon adenocarcinoma. Canadian Journal of Ophthalmology/Journal Canadien d'Ophtalmologie. 2013;48(5):e116-e20.
Rahimy E, Sarraf D. Paraneoplastic and non-paraneoplastic retinopathy and optic neuropathy: evaluation and management. Survey of Ophthalmology. 2013;58(5):430-58.
https://doi.org/10.1016/j.survophthal.2012.09.001
Urai Y, Matsumoto K, Shimamura M, Ikeda K, Tsukaguchi M, Deguchi K, et al. Paraneoplastic necrotizing myelopathy in a patient with advanced esophageal cancer: an autopsied case report. Journal of the Neurological Sciences. 2009;280(1-2):113-7.
https://doi.org/10.1016/j.jns.2009.02.324
Shimoda T, Koizumi W, Tanabe S, Higuchi K, Sasaki T, Nakayama N, et al. Small-cell carcinoma of the esophagus associated with a paraneoplastic neurological syndrome: a case report documenting a complete response. Japanese Journal of Clinical Oncology. 2006;36(2):109-12.
https://doi.org/10.1093/jjco/hyi241
Macdonell RA, Rich JM, Cros D, Shahani BT, Ali HH. The Lambert-Eaton myasthenic syndrome: a cause of delayed recovery from general anesthesia. Archives of Physical Medicine and Rehabilitation. 1992;73(1):98-100.
Pautas E, Cherin P, Wechsler B. Polymyositis as a paraneoplastic manifestation of rectal adenocarcinoma. The American Journal of Medicine. 1999;106(1):122-3.
Katzka DA, Farrugia G, Arora AS. Achalasia secondary to neoplasia: a disease with a changing differential diagnosis. Diseases of the Esophagus: official journal of the International Society for Diseases of the Esophagus. 2012;25(4):331-6.
https://doi.org/10.1111/j.1442-2050.2011.01266.x
Taverna JA, Babiker HM, Yun S, Bishop MC, Lau-Braunhut S, Meyer PN, et al. The great masquerader of malignancy: chronic intestinal pseudo-obstruction. Biomarker Research. 2014;2(1):23-8
https://doi.org/10.1186/s40364-014-0023-y
Kashyap P, Farrugia G. Enteric autoantibodies and gut motility disorders. Gastroenterol Clin North Am 2008;37(2):397-410.
https://doi.org/10.1016/j.gtc.2008.02.005
Argyriou KN, Peters M, Ishtiaq J, Enaganti S. A rare case of paraneoplastic syndrome presented with severe gastroparesis due to ganglional loss. Case reports in Medicine. 2012.
https://doi.org/10.1155/2012/894837
Brown WR, Dee E. Dysphagia in a patient with recurrent small-cell lung cancer. Gastroenterology. 2013;144(1):34, 252-3.
https://doi.org/10.1053/j.gastro.2012.08.007
Ebert EC. Gastrointestinal and hepatic manifestations of systemic diseases. In: Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and fordtran's gastrointestinal and liver disease: Pathophysiology, diagnosis, management. United States: Elsevier; 2016:579-616e14.
Donthireddy KR, Ailawadhi S, Nasser E, Schiff MD, Nwogu CE, Nava HR, et al. Malignant gastroparesis: pathogenesis and management of an underrecognized disorder. J Supp Oncol. 2007;5(8):355-63.
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