Guía de práctica clínica para el diagnóstico y tratamiento de la infección por helicobacter pylori en adultos: actualización 2025

Autores/as

DOI:

https://doi.org/10.22516/25007440.1458

Palabras clave:

Helicobacter pylori, Diagnóstico, Terapia, Guía de práctica clínica

Resumen

Introducción: en 2015, la Asociación Colombiana de Gastroenterología (ACG) publicó la guía de práctica clínica (GPC) para el diagnóstico y tratamiento de la infección por Helicobacter pylori en adultos. En 2025, la Asociación realizó el proceso de actualización de esta guía de acuerdo con la necesidad de actualización de las estrategias diagnósticas y terapéuticas, adaptadas a la realidad microbiológica local y a las características clínicas de la población.

Materiales y métodos: el comité de guías de la ACG con el acompañamiento de epidemiólogos realizó la actualización con base en una revisión sistemática de recomendaciones de práctica y metaanálisis siguiendo las directrices de la metodología GRADE. En esta versión corta de la GPC-actualización 2025 se presenta un breve resumen de la evidencia que apoya las recomendaciones. El detalle del proceso de actualización puede consultarse en la versión completa disponible en www.gastrocol.com.

Resultados: la actualización de 2025 presenta recomendaciones sobre indicaciones de tratamiento para curar el H. pylori y prevenir otras patologías, métodos diagnósticos invasivos y no invasivos, alternativas de tratamiento en las diferentes líneas y consideraciones particulares como zonas de alta resistencia, alergia a la penicilina y poblaciones especiales.

Conclusión: un adecuado diagnóstico y tratamiento de la infección por H. pylori es esencial dado su rol como factor de riesgo en condiciones como gastritis crónica, úlceras pépticas, linfoma MALT gástrico y adenocarcinoma del estómago.

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Biografía del autor/a

William Alberto Otero Regino, Universidad Nacional de Colombia

Universidad Nacional de Colombia, Centro de Gastroenterología y Endoscopia

Alba Alicia Trespalacios Rangel, Pontificia Universidad Javeriana

Doctora en Ciencias Biológicas. Magister en Microbiología, BLC. Fellow in Gastroenterology Research Baylor College of Medicine - USA. Decana Facultad de Ciencias y Profesora Titular II del Departamento de Microbiología - Facultad de CIencias; Pontificia  Universidad Javeriana. Directora Línea de investigación: caracterización molecular de Helicobacter pylori e Investigadora Senior de MinCiencias. Bogotá, Colombia. 

Hernando Marulanda Fernandez, Centro de gastroenterología

Médico, especialista en Medicina Interna y Gastroenterología Universidad Nacional de Colombia. Especialización en Ultrasonido Endoscópico (Universitat Oberta de Catalunya, España). Especialista en Docencia Universitaria y Magíster en Educación Fundación Universitaria de Ciencias de la Salud (FUCS). Miembro del Grupo Colombiano de Investigación en Helicobacter pylori. Gastroenterólogo en Hospital Central de la Policía, Hospital de Kennedy y Centro de Gastroenterología. Bogotá, Colombia.

Diego Fernando Rojas Gualdrón, Universidad CES

Epidemiólogo y bioestadístico. Profesor titular, Facultad de Medicina, Universidad CES. Medellín, Colombia.

Diego Mauricio Aponte Martín, Clínica Reina Sofía

Médico Internista, Epidemiólogo y Gastroenterólogo. Jefe de Posgrado de Gastroenterología Fundación Universitaria Sanitas. Expresidente de la Asociación Colombiana de Endoscopia Digestiva y Presidente de la Asociación Colombiana de Gastroenterología. Bogotá, Colombia.

Raúl Antonio Cañadas Garrido, Hospital Universitario San Ignacio

Médico internista y gastroenterólogo. Jefe unidad de gastroenterología. Hospital Universitario San Ignacio-Universidad Javeriana. Ex-presidente Asociación Colombiana de Endoscopia Digestiva. Bogotá, Colombia.

Jaime Andrés Ibarra Burgos, Universidad CES

Médico internista, epidemiólogo clínico. Facultad de Medicina, Universidad CES. Medellín, Colombia.

Juan David Linares Ramírez, Fundacion Universitaria Inpahu

Médico y cirujano general. Universidad del Rosario. Gastroenterólogo y endoscopista. Fundación Universitaria Sanitas. Gastroenterólogo Clínicas Colsanitas. Bogotá, Colombia.

Alejandro Concha Mejía, Clínica del Country

Médico Internista, gastroenterólogo, endoscopista y epidemiólogo. Jefe de Gastroenterología Clínicas del Country y la Colina. Coordinador de Gastroenterología, Clinicentro Salitre Colsanitas. Gastroenterólogo, Fundación Clínica Shaio. Bogotá, Colombia.

Luis Carlos Sabbagh, Fundación Universitaria Sanitas

M.D. FASGE. Jefe de Gastroenterología Clínica Reina Sofía y Clínica Universitaria Colombia. Director de Postgrado en Gastroenterología-Fundación Universitaria Sanitas. Director Centro de Entrenamiento de la World Gastroenterology Organization (WGO). Bogotá, Colombia.

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Guía de práctica clínica para el diagnóstico y tratamiento de la infección por helicobacter pylori en adultos: actualización 2025

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2025-11-10

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Otero Regino, W. A., Trespalacios Rangel, A. A., Marulanda Fernandez, H., Rojas Gualdrón, D. F., Aponte Martín, D. M., Cañadas Garrido, R. A., … Sabbagh Sanvicente , L. C. (2025). Guía de práctica clínica para el diagnóstico y tratamiento de la infección por helicobacter pylori en adultos: actualización 2025. Revista Colombiana De Gastroenterología, 40(Supl. 4), 3–32. https://doi.org/10.22516/25007440.1458