Case Series: The Gastric Face of Lipid Deposits
DOI:
https://doi.org/10.22516/25007440.1244Keywords:
Xantoma, Helicobacter pylori, atrophic gastritis, metaplasiaAbstract
Xanthoma is a benign lesion associated with lipid metabolism, commonly manifesting in various areas of the body. Gastric xanthomas, often incidentally identified during endoscopic procedures, are histopathologically characterized by the presence of foamy histiocytes in the gastric mucosa. Their prevalence ranges from 0.23% to 7%, with the antrum being the most frequently affected site and a clear association with increasing age.
This study presents 20 cases of patients diagnosed with gastric xanthoma between 2016 and early 2024. Chronic gastritis was observed in 90% of patients, intestinal metaplasia in 20%, mild atrophy in 25%, and low-grade dysplasia in only one case (5%). In addition, Helicobacter pylori infection was detected in 30% of the cases. The importance of conducting prospective research is emphasized to better understand the relationship between gastric mucosal alterations and gastric xanthomas, with a particular focus on early detection of gastric cancer.
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